There are three versions of the "standard" Time Machine, 40, 50, and 60. The 50 is around 600 or so squares and aimed at the LA-46, tigre 51, etc.
I have built and flown all three versions, and the bigger they get, the better they fly. I commented on this fact once to Jose Modesto at a Brodaks contest once, and he grinned and said that the full size Patternmaster was that much better then the TM 60. The 40 and 50 do fly tolerably well, but it seems that a pure CAD or photocopier scaledown does not seem quite right, like something in the moments gets lost in the translation. I think in the realm of a 40 size airplane any good classic design would fly just as well as the Time Machine 40. I would hesitate to try a DS 40 or Fox 35 in a TM 40, I think the thick wing would give the smaller engines more than they could handle. Down in Texas there is a cat named Jim Svitko who has been flying Time Machines longer than I have, and he has gotten the 40 size ones to work really well with the LA-46. His planes have his own design fuselage and the overall effect is much better looking than the stock Time Machine.
I'd like to try a full size Patternmaster someday, but it will have to wait till Randy gets more PA-75s made. After flying Banjock's Patternmaster sized Vista with the 75, I think putting any less motor in a Patternmaster (well, ok, less than a PA-65 SE) would be tantamount to a crime since you could never tap the planes full potential.