Both the Nelson and the Turbo plugs "get the threads out of the combustion chamber" which can greatly(1000 rpm) improve the engine power. It eliminates one more variable in the engine operation. How tight the plug fits is no longer an issue.
Another potentially big variable is the fit between the head and the cylinder. If the head plugs into the cylinder the fit is critical. A couple thousandths too loose can cost 500 rpm and change how the engine runs. The proper fit is just enough clearance that the head will just fit into the cylinder when it is put in square.
If the head sits on top of the cylinder- some Supertigres, Magnum, ASP- make sure the gaskets are correctly sized. They should be sized to the bore and centered on it so there isn't any small gap around the cylinder between it and the head. The idea is to eliminate any crevices in the cylinder/head area.
Turbo plugs use an 8mm thread. I saw a post on rcuniverse a few years back about fitting turbo plugs into a standard head. One of the standard, double ended, center spotting drills is the right size and angles to drill out the threads and for the tapered area. It leaves enough meat to then tap the hole 8mm for the turbo plug. I forget the actual sizes so you'll have to look the up your self. Best done on a small mill, but several folks were able to do it on a drill press. Just take care to not reposition the head when switching between the drill and tap so everything stays centered.