Randolph says 50% max if you care about blush.
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Randolph makes enamel, dope, and polyurethane paints. Each product has its own sensitivity to humidity with dope being the most sensitive to humidity, enamels next less sensitive, and 2-part polyurethanes being the least sensitive. I spray dope in a temperature range of about 65 to 95 degrees F, and in a humidity range of about 65 to maybe 70% maximum. I will spray in low humidity such as 10% RH and temperature in the range shown above and add butyrate retarder as needed. This is for full-scale airplanes as well as models. You just have to try spraying & adjust the mix & technique as you go.
Enamels can be adjusted somewhat by varying the speed of the reducer, and for acrylic enamels a hardener is available that improves the gloss & chemical resistance appreciably. Two-part polyurethanes are the easiest to work with in widely varying temperature/humidity conditions; various speed reducers are available along with various speed catalysts as well as accelerators to accelerate the cure time.
Rustoleum (spray cans) is an excellent product but there is not anything you can do to vary the paint mix. You just have to pick your conditions and you can end up with excellent results.