It has been found out that when everything is petty straight, that having the plane fly as close to tangent to the flight path makes for the best overall tension. That is why so many top echelon pilots use a 0-0-0 set up. I still like a degree or two of engine out thrust (mainly to make sure I don't have *in* thrust! LOL!!
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I also thought the 0-0-0 thing was fairly universal among The Stunt Gods, but recently I have seen some interesting exceptions.
I got a set of plans for the Chinese F2B Skywriter and was surprised to see engine offset--a lot of engine offset. The engine installation is sidewinder, but I don't think there is any connection.
Ted Fancher has said that he builds downthrust into his planes, and Bob Whitely says that a combination of down and out thrust results in a more stable flying airplane. I don't have the quotes in front of me, so don't want to list exact numbers, cuz sure as I do they will be wrong.

The fact that very small angles like this are hard to measure doesn't make it easier, but other things do help make it easier, such as Windy clamp mounts (for downthrust on profiles or outthrusht on upright/inverted engines) or R/C mounts which can be shimmed between the mount and firewall with slightly angled shims, allowing adjustments and experimentation.
Kim Mortimore