Rarely does one get a chance to do an experiment that simply changes a single variable. You can't build two "identical" planes unless they are from a FULLY tooled set of moulds. In the case of the test I did, that could be very difficult to do as some of the moulds would have to change.
What I did was take my OLD '97 Impact that is nothing more than a test bed now, and since the nose ring was long gone, it afforded me the opportunity. I built a motor adaptor that located the motor in the "plans" vertical location, and that same adaptor would also allow the motor to be moved down to the wing centerline vertical location.
To be sure the results would not be my wishful thinking, I recruited Chris Cox to fly it as well. I did not fly it until he was present for the test. It started by flying it in the "plans" location. We both thought is was still a good flying plane. Then the motor was changed to the inline location, and we both reflew it. I flew it first, and I usedmy best poker face not to influence Chris.
After he landed, he wanted to know WHY I didn't like it!! Yes, I liked it. My poker face worked.
What did it do better: tracked better in level flight, tracked better in the wingover, round loops were easier, square corners more consistent. This carried through in all maneuvers. We agreed that there was not a single thing made worse by moving the motor inline.
Chris went home and started on a new inline plane, as did I. Neither of us has build a non inline plane since.
Moving the motor to the inline position changes two variables, that being the thrust line, and the mass distribution is different. It would be quite difficult to separate these two variables. But the result is such that it is of no concern to me to test more to find out.
As stated earler, this was done with a 16g 12 inch 3 blade prop. Heavier prop could make some difference.