I'm trying to cut down on answers that involve lots of supposition, but you asked in the other thread, so:
For anything other than a Yatsenko, yes, in general, changing line diameter or the length, or even significantly changing the speed of the aircraft would change the desired leadout position. But I don't know why the Yatsenkos feel they can ship with fixed leadouts, nor do I know if they've done some other magic -- hence, no answers so far.
Maybe someone who does fly Yatsenkos, or are otherwise familiar with them, can answer?