There are two problems:
1/ As Tim already wrote, the prop better reacts to load (better thrust at lower speed) compared to EDF. So the EDF will be probably worse, but you can still use some active controll. The question comes, how large and heavy EDF can create the same static thrust like the prop, I affarid you will come to heavier power train.
2/ The wing, flaps and elevator of the model with ususla prop is in high speed air also when models slows down, but model with EDF will change properties regarding actual speed, I affarid it will be far worse and difficult to control (I mean for PA).