PaulT,
Looking at the Cutoff tab it is set for auto lipo voltage 4Volts and 3 volts per cell. I am thinking that this might be causing some conflict in the ESC, I like to set mine for a voltage cutoff of 3.2 volts.
I also like to set the current cutoff to hard fast. The settings you have should not cause a problem for normal start and flight. I had a ship get caught in wet grass on takeoff and flip over, the motor just kept trying to pull more current since the ship wasn't stuck in the ground. This caused the motor to fry, now have hard fast current cutoff.
Best, DennisT