Hi James,
   To answer your question yes and no. If the motor is a brushed motor than yes, you need to break it in (seat the brushes). Chances are you will be using a brushless motor which requires NO break-in.

   It is also a good practice to cycle your lipo batteries (about 5 times) at a lower current draw than you will be using in flight. Most of the packs used in PA are 3700-4200mah, so discharging them at 12-20amps is what you should aim for. This helps weed out any possible bad cells and gives you a chance to balance the cells making sure they all are 100% functional.

   NiCd or NiMH cells (less likely to be used) should be charged at a very low current before their first flight. A good first charge is 1/10 of their capacity. This helps balance the cells (no one cell is over/under charged).

   Normally one question gets answered and 2 more are born, so we will await you next question with open ears (or open eyes).     

Mike