I also usually face the uniflow inlet vent to the wind. However, if using muffler pressure, it doesn't much matter.
Siphoning could be a problem, but the uniflow inlet tube is the only opening to the air outside the model, and then only if it is NOT getting muffler pressure. The uniflow system relies on drawing the fuel down the vent tube to the interior opening. Without the engine drawing fuel, the levels inside and outside that tube would be the same. The engine draws a slight negative (guage) pressure inside the tank shell.
With any kind of pressure fed into the shell it doesn't seem to me that uniflow or any other vent type makes much difference. Even with the very low pressure from a chip or tube-type muffler, siphoning would have to not only raise the fuel above the equal 'stand-pipe' height, but also against the muffler pressure provided.
A small thought: I've had better runs, more simply, by connecting muffler pressure to the overflow tube and capping the external uniflow tube. At least, the distance to the overflow tube is greater than from the pickup to the uniflow internal end. NO chance of bubbles entering the fuel supply tube. The overflow tube usually comes up to the inside,front top of the tank. The model spends more time upright than inverted, for one thing, and the fuel surface resulting from the combination of gravity and centrifugal loads moves away from the inside tank wall quite early in a flight. The pressure dumps into 'air' space, not out a tube end near the fuel pickup.
Now, diesel fuels can fizz up a lot more than glow fuels, and that can look like siphoning. That's another whole story, and not much relevant to the original question...