Hu:
Will this harm the engine?
No. It will harm the performance of the airplane, but not the engine. The "don't ever run it rich!!!!!" advice stems from George Aldrich, who ruined his first ST X29 ABC because he thought it was way too tight, and proceeded to take out all the taper to loosen it up on his Sunnen Honing machine. Of course it was worthless after that. Then he got the idea behind it, and then went hard-over the other way, setting his engines up tighter and with more taper, which might have been a good idea for a racing engine (some of which *glow a dull red* when they are running), it was a disastrous idea for a stunt engine, since it never got hot enough to loosen up. You probably can damage a ST X29 running it rich, and I know that many of the GMA ABC engines were eventually damaged by running them normally for stunt. Interestingly, the cylinder and piston was durable enough, but the crank wasn't - jamming the piston into the taper with it *squeaking in flight*, 240 times a second, was a bit stressful.
The 40LA doesn't have enough taper nor is it too tight to run in a 4-stroke. You probably don't want to, for performance reasons, but it almost certainly won't hurt anything.
Brett