EI168,
I suspect that inverted installations started mainly for a sleeker look. The engines, once running, should act the same upright and inverted, since we fly both ways in the stunt pattern. Tank height may - usually does - need tweaking to get it to do that, but once you have that, it should be dependable. Sidewinder tank mount height for most engines is usually close to centered on the venturii (or shaft) centerline height, but Fox 35s on profiles DO like the uniflo inside vent around 1/4" higher (when right side up.)
There is a difference between fuel head conditions for upright/inverted mount and for sidewinders. The tank width in a built-up fuselage model (upright or inverted engine) is generally centered on the engine crankcase/shaft. That's at least one inch further inboard than a profile tank CAN be mounted, unless you dig out the outboard doubler and sink the inboard side of the tank further inboard... To get the same "centered" condition as on a built-up, upright or inverted mount fuselage, you might have to cut away the inboard doubler to clear the tank, too. Even then, there might be a difference in how it runs, usually blamed on the way fuel pools up inside the crankcase when profile mounted.
Hopkins' inboard sidewider engine/inboard tank layout models had a GREATER fuel head at the start of a flight, which gradually decreased as fuel burned off. An outboard/outboard layout has the opposite condition - largest positive fuel head at the start of a flight, decreasing all the way as fuel is used up. And, unless you carve up the outboard doubler, the out/out layout starts with the inboard wall about 1/2" further outboard than the shaft centerline. Hopkins' inboard/inboard layout's LEAST positive fuel head distance is about the same 1/2" to the high side.
BTW, I know that Bill H. probably didn't originate the inboard/inboard configuration, but since his nice flying foamies were mentioned in here, refer to them...
A proper uniflow tank setup can make enough difference that actual fuel head distances don't affect feed. (Fuel head distance is the height, measured along the direction of "gravity" from the fuel surface to the fuel jet - NVA outlet orifice - which we usually don't think much about.) The big secret of uniflow tanks may be that the "surface" open for venting is where vent air enters the tank shell volume, near the outboard wall. That then becomes the fuel surface reference involved in figuring "gravity head"...
The direction of the "gravity" force the fuel feels is due to the combination of simple gravity - 1 g, aimed at the center of the earth whatever the position of the model is - and the centrifugal force load, 3 g or so (generally accepted for stunt or sport stunt models) aimed horizontally outwards. (The axis for the CF radius at any given time is the vertical line through the center of the flight path hemisphere.) So, the "effective gravity" aims out about three, and down one - at least in level flight. If the 1g and 3g estimates are exactly right at a given instant, that's aiming about 19.5° below horizontal, and out from the center, with a force of about 3.15 g. As the model flies at different heights and through different shapes, the tank, itself, is moved around, and the g from maneuvering loads adds in for finding the direction of "instantaneous g" and how many g it actually is at that instant.
The uniflow tube end is usually so near the fuel pickup "height" in all situations that g on the fuel itself means little. However, if the whole tank is too high or too low in/on the fuselage, that becomes another gravity head condition. Uniflow tanks are more sensitive to tank height than the old over/under open vented monsteres, but are so much nicer when they are right.
(edited because it posted itself before I was ready - oops...)